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Article

Relationship of 5-HTTLPR genotypes and depression risk in the presence of trauma in a female twin sample.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2007

Chorbov Vesselin M, Lobos Elizabeth A, Todorov Alexandre A, Heath Andrew C, Botteron Kelly N, Todd Richard D

Abstract excerpt

Several studies have implicated an insertion/deletion polymorphism in the promoter region of the serotonin transporter gene (SLC6A4; 5-HTT) in the development of mood disorders. In the present study of a sample of 247 young adult female twins from Missouri, we examine whether this polymorphism interacts with the effect of adverse life events to increase risk for developing depression. We found a significant...

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PMID: 17455215
DOI: 10.1002/ajmg.b.30534

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HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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