Article
Effect of OPRM1 and stressful life events on symptoms of major depression in African American adolescents.
Journal of affective disorders - 1 Jun 2014
Swann Gregory, Byck Gayle R, Dick Danielle M, Aliev Fazil, Latendresse Shawn J, Riley Brien, Kertes Darlene, Sun Cuie, Salvatore Jessica E, Bolland John, Mustanski Brian
Abstract excerpt
BACKGROUND: In a community sample of low-income African American adolescents, we tested the interactive effects of variation in the mu 1 opioid receptor (OPRM1) gene and the occurrence of stressful life events on symptoms of depression. METHOD: Interactive effects of 24 OPRM1 simple nucleotide polymorphisms (SNP) and adolescent report of stressful life events on depression were tested using multilevel...
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