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Article

[Study of the Toll-like receptor 4 gene polymorphisms in diseases presenting with subclinical and chronic inflammation].

Orvosi hetilap - 13 Nov 2011

Reismann Péter

Abstract excerpt

UNLABELLED: Toll-like receptor 4, a central mediator of the innate immune response has been shown to play an important role not only in the defense mechanism against microorganism, but also other non-infectious inflammatory diseases such as atherosclerosis. The Asp299Gly and Thr399Ile, which are common co-segregation polymorphisms of the Toll-like receptor 4 gene have been shown to be associated with increased...

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Identifiers

PMID: 22030363
DOI: 10.1556/OH.2011.29243

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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[Study of the Toll-like receptor 4 gene polymorphisms in diseases presenting with subclinical and chronic inflammation].PMID 22030363Read ↗

[Polymorphisms of the Toll-like receptor 4 gene and their potential role in infectious diseases and chronic inflammatory disorders].Semantic proximity Read ↗

Lack of association between chronic periodontitis and the Toll-like receptor 4 gene polymorphisms in a Czech population.Semantic proximity Read ↗

Asp299Gly and Thr399Ile genotypes of the TLR4 gene are associated with a reduced prevalence of diabetic neuropathy in patients with type 2 diabetes.Semantic proximity Read ↗

TLR4 polymorphisms seem not to be associated with prediabetes and type 2 diabetes but predispose to diabetic retinopathy; TLR4 polymorphisms in glucose continuum.Semantic proximity Read ↗

Toll-like receptor (TLR) 2 and 4 mutations in periodontal disease.Semantic proximity Read ↗

Polymorphisms of Toll-Like Receptor 4 as a Risk Factor for Periodontitis: Meta-Analysis.Semantic proximity Read ↗

TLR2 Arg753Gly, TLR4 Asp299Gly and Thr399Ile gene polymorphisms are not associated with chronic periodontitis in a Turkish population.Semantic proximity Read ↗

Rarity of TLR4 Asp299Gly and Thr399Ile polymorphisms in the Korean population.Semantic proximity Read ↗

TLR4 gene polymorphisms: evidence for protection against type 2 diabetes but not for diabetes-associated ischaemic heart disease.Semantic proximity Read ↗

Chronic periodontal disease is associated with single-nucleotide polymorphisms of the human TLR-4 gene.Semantic proximity Read ↗

Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes.Semantic proximity Read ↗

Polymorphisms of TLR4 but not CD14 are associated with a decreased risk of aggressive periodontitis.Semantic proximity Read ↗

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