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Article

Novel SNPs of WNK1 and AKR1C3 are associated with preeclampsia.

Gene - 20 Aug 2018

Sun Cheng-Juan, Li Lin, Li Xueyan, Zhang Wei-Yuan, Liu Xiao-Wei

Abstract excerpt

Preeclampsia is a hypertensive disorder of pregnancy and is one of the most common causes of poor perinatal outcomes. Preeclampsia increases the risk of hypertension in the future. Variants of WNK1 (lysine deficient protein kinase 1), ADRB2 (β2 adrenergic receptor), NEDD4L (ubiquitin-protein ligase NEDD4-like), KLK1 (kallikrein 1) contribute to hypertension, and AKR1C3 (aldo-keto reductase family1 member C3), is...

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Source

Identifiers

PMID: 29777907
DOI: 10.1016/j.gene.2018.05.055

Genes

WNK1
ADRB2
KLK1
NEDD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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