Article
Polymorphisms in NR5A2, gene encoding liver receptor homolog-1 are associated with preterm birth.
Pediatric research - 1 May 2016
Kaluarachchi Dinushan C, Momany Allison M, Busch Tamara D, Gimenez Lucas G, Saleme Cesar, Cosentino Viviana, Christensen Kaare, Dagle John M, Ryckman Kelli K, Murray Jeffrey C
Abstract excerpt
BACKGROUND: Preterm birth (PTB) is a major cause of neonatal mortality and morbidity. There is strong evidence of genetic susceptibility. Objective of this study was to identify genetic variants contributing to PTB. METHODS: Genotyping was performed for 24 single nucleotide polymorphisms (SNPs) in 4 candidate genes (NR5A2, FSHR, FOXP3, and SERPINH1). Genotyping was completed on 728 maternal triads (mother and...
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