Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The KIR2DS2/DL2 genotype is associated with adult persistent/chronic and relapsed immune thrombocytopenia independently of FCGR3a-158 polymorphisms.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jan 2012

Nourse Jamie P, Lea Rod, Crooks Pauline, Wright Gillian, Tran Huyen, Catalano John, Brighton Tim, Grigg Andrew, Marlton Paula, Gandhi Maher K

Abstract excerpt

Adult immune thrombocytopenia (ITP) is a heterogeneous disease and its immunobiology is incompletely understood. Establishing associations between candidate genes and ITP susceptibility may provide insight into pathogenesis. Previous studies have associated overrepresentation of FCGR3a-V158 allele with pediatric ITP. We prospectively accrued DNA from 102 adult patients with persistent/chronic or relapsed primary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Chronic Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Purpura, Thrombocytopenic, Idiopathic

Share to Receptors, IgG

Share to Receptors, KIR

Share to Receptors, KIR2DL2

Share to Recurrence

Share to Young Adult

Source

Identifiers

PMID: 22024796
DOI: 10.1097/MBC.0b013e32834d7ce3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The KIR2DS2/DL2 genotype is associated with adult persistent/chronic and relapsed immune thrombocytopenia independently of FCGR3a-158 polymorphisms.PMID 22024796Read ↗

The presence of KIR2DS5 confers protection against adult immune thrombocytopenia.Semantic proximity Read ↗

Deciphering the genetic basis of immune thrombocytopenia: current evidence for genetic predisposition in adult ITP.Semantic proximity Read ↗

HLA profile in paediatric ITP: Comparison with healthy controls and prognostic implications.Semantic proximity Read ↗

STAT1 single nucleotide polymorphisms and susceptibility to immune thrombocytopenia.Semantic proximity Read ↗

FcγRIIa and FcγRIIIa polymorphisms in childhood primary immune thrombocytopenia: implications for disease pathogenesis and outcome.Semantic proximity Read ↗

FcγRIIIa polymorphism in pediatric immune thrombocytopenia: impact on clinical course and outcomeSemantic proximity Read ↗

Stromal-derived factor-1 gene variations in pediatric patients with primary immune thrombocytopenia.Semantic proximity Read ↗

Clinical features and major histocompatibility complex genes as potential susceptibility factors in pediatric immune thrombocytopenia.Semantic proximity Read ↗

Inborn Errors of Immunity in Children and Adolescents with Immune ThrombocytopeniaSemantic proximity Read ↗

Toll-Like Receptor 9 (TLR9) Gene C/T (rs352140) Polymorphisms in Adult Primary Immune Thrombocytopenia.Semantic proximity Read ↗

PTPN22 gene polymorphism as a genetic risk factor for primary immune thrombocytopenia in Egyptian children.Semantic proximity Read ↗

Genetic variants in canonical Wnt signaling pathway associated with pediatric immune thrombocytopenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.