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Article

The biological significance of TLR3 variant, L412F, in conferring susceptibility to cutaneous candidiasis, CMV and autoimmunity.

Autoimmunity reviews - 1 Mar 2012

Nahum Amit, Dadi Harjit, Bates Andrea, Roifman Chaim M

Abstract excerpt

OBJECTIVE: Toll-like receptors, a major component of the innate immune system, play an important role in the initial response against pathogens. Genetic abnormalities in some receptors like TLR2, TLR3 and TLR4 have been associated with susceptibility to fungal and viral infections while other abe...

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Source

Identifiers

PMID: 22024499
DOI: 10.1016/j.autrev.2011.10.007

Genes

TLR3
TLR2
TLR4
TLR7
TLR9

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22024499-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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The biological significance of TLR3 variant, L412F, in conferring susceptibility to cutaneous candidiasis, CMV and autoimmunity.PMID 22024499Read ↗

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