Article
A new concept to reveal protein dynamics based on energy dissipation.
PloS one - 1 Jan 2011
Ma Cheng-Wei, Xiu Zhi-Long, Zeng An-Ping
Abstract excerpt
Protein dynamics is essential for its function, especially for intramolecular signal transduction. In this work we propose a new concept, energy dissipation model, to systematically reveal protein dynamics upon effector binding and energy perturbation. The concept is applied to better understand the intramolecular signal transduction during allostery of enzymes. The E. coli allosteric enzyme, aspartokinase III,...
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