Article
Protein dynamics and motions in relation to their functions: several case studies and the underlying mechanisms.
Journal of biomolecular structure & dynamics - 1 Jan 2014
Yang Li-Quan, Sang Peng, Tao Yan, Fu Yun-Xin, Zhang Ke-Qin, Xie Yue-Hui, Liu Shu-Qun
Abstract excerpt
Proteins are dynamic entities in cellular solution with functions governed essentially by their dynamic personalities. We review several dynamics studies on serine protease proteinase K and HIV-1 gp120 envelope glycoprotein to demonstrate the importance of investigating the dynamic behaviors and molecular motions for a complete understanding of their structure-function relationships. Using computer simulations...
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