Article
A new powerful method for site-specific transgene stabilization based on chromosomal double-strand break repair.
PloS one - 1 Jan 2011
Tkachuk Artem, Kim Maria, Kravchuk Oksana, Savitsky Mikhail
Abstract excerpt
Transgenic insects are a promising tool in sterile insect techniques and population replacement strategies. Such transgenic insects can be created using nonautonomous transposons, which cannot be transferred without a transposase source. In biocontrol procedures where large numbers of insects are released, there is increased risk of transgene remobilization caused by external transposase sources that can alter...
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