Article
Comprehensive characterization of a transgene insertion in a highly repetitive, centromeric region of Anopheles mosquitoes.
Pathogens and global health - 1 May 2023
Vitale Matteo, Leo Chiara, Courty Thomas, Kranjc Nace, Connolly John B, Morselli Giulia, Bamikole Christopher, Haghighat-Khah Roya Elaine, Bernardini Federica, Fuchs Silke
Abstract excerpt
The availability of the genomic sequence of the malaria mosquito Anopheles gambiae has in recent years sparked the development of transgenic technologies with the potential to be used as novel vector control tools. These technologies rely on genome editing that confer traits able to affect vectorial capacity. This can be achieved by either reducing the mosquito population or by making mosquitoes refractory to the...
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