Article
An efficient strategy for producing a stable, replaceable, highly efficient transgene expression system in silkworm, Bombyx mori.
Scientific reports - 5 Mar 2015
Long Dingpei, Lu Weijian, Zhang Yuli, Bi Lihui, Xiang Zhonghuai, Zhao Aichun
Abstract excerpt
We developed an efficient strategy that combines a method for the post-integration elimination of all transposon sequences, a site-specific recombination system, and an optimized fibroin H-chain expression system to produce a stable, replaceable, highly efficient transgene expression system in the silkworm (Bombyx mori) that overcomes the disadvantages of random insertion and post-integration instability of...
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