Article
Involvement of mitochondrial ribosomal proteins in ribosomal RNA-mediated protein folding.
The Journal of biological chemistry - 23 Dec 2011
Das Anindita, Ghosh Jaydip, Bhattacharya Arpita, Samanta Dibyendu, Das Debasis, Das Gupta Chanchal
Abstract excerpt
The peptidyl transferase center of the domain V of large ribosomal RNA in the prokaryotic and eukaryotic cytosolic ribosomes acts as general protein folding modulator. We showed earlier that one part of the domain V (RNA1 containing the peptidyl transferase loop) binds unfolded protein and directs it to a folding competent state (FCS) that is released by the other part (RNA2) to attain the folded native state by...
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