Article
The role of expansion segment of human ribosomal protein L35 in nuclear entry, translation activity, and endoplasmic reticulum docking.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Jun 2008
Chen In-Jay, Wang I-Ann, Tai Lin-Ru, Lin Alan
Abstract excerpt
The phylogenic alignment of homologous L35 protein suggests that human large subunit ribosomal protein L35 carries a 54 aa eukaryotic expansion segment (ES) at the C-terminal end. Within this ES, the first 25 amino acid residues were found to be essential for the nuclear import of the protein. The last 29 residues of the ES were shown to be uninvolved in the ribosome's structural and translational functions,...
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