Article
The CREM gene is involved in genetic predisposition to inflammatory bowel disease in the Tunisian population.
Human immunology - 1 Dec 2011
Bouzid Dorra, Fourati Hajer, Amouri Ali, Marques Isabel, Abida Olfa, Haddouk Samy, Ben Ayed Mourad, Tahri Nabil, Penha-Gonçalves Carlos, Masmoudi Hatem
Abstract excerpt
The identification of susceptibility genes for inflammatory bowel disease (IBD) is key to understanding pathogenic mechanisms. Recently, the results of genetic association studies have highlighted many loci that are shared among several autoimmune diseases. We aimed to study the genetic epidemiology of polymorphisms in specific genes previously associated with other autoimmune diseases, namely the CREM, STAT4,...
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