Article
IRF5, but not TLR4, DEFB1, or VDR, is associated with the risk of ulcerative colitis in a Han Chinese population.
Scandinavian journal of gastroenterology - 1 Oct 2013
Li Pan, Lv Hong, Yang Hong, Qian Jia-Ming
Abstract excerpt
OBJECTIVE. IRF5, TLR4, DEFB1, and VDR genetic variations have been associated with ulcerative colitis (UC) in several European patient cohorts. As distinct genetic backgrounds may play a role in different ethnicities, we evaluated the effects of single-nucleotide polymorphisms (SNPs) in these genes and their interactions in UC patients of Han Chinese descent. MATERIAL AND METHODS. DNA samples from 300 UC patients...
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