Article
Analysis of TNFα promoter SNPs and the risk of cervical cancer in urban populations of Posadas (Misiones, Argentina).
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jan 2012
Badano Ines, Stietz Silvina M, Schurr Theodore G, Picconi Alejandra M, Fekete Daniel, Quintero Ivana M, Cabrera Maia D E, Campos Rodolfo H, Liotta Javier D
Abstract excerpt
BACKGROUND: Human papillomavirus (HPV) plays a central role in cervical cancer development. However, only a small fraction of infected women develop the disease. Additional risk factors, including SNPs in immune system and cytokine genes, are likely to be important determinants. OBJECTIVE: We investigated the potential role of cytokine TNF-α promoter SNPs (TNFα-375A, TNFα-307A, TNFα-243A, and TNFα-237A) in the...
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