Article
TNF-α and IL-10 promoter polymorphisms, HPV infection, and cervical cancer risk.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2012
Barbisan Gisela, Pérez Luis Orlando, Contreras Anahí, Golijow Carlos Daniel
Abstract excerpt
Although the implication of genetic factors in cervical cancer development remains to be elucidated, accumulative epidemiological evidence suggests that polymorphisms of cytokine genes may be involved in the etiology of cervical carcinoma. Tumor necrosis factor alpha (TNF-α) and interleukin-10 (IL-10) are two multifunctional cytokines implicated in inflammation, immunity, and cellular organization, and were...
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