Article
TNF-alpha promoter polymorphisms and susceptibility to human papillomavirus 16-associated cervical cancer.
The Journal of infectious diseases - 15 Mar 2005
Deshpande Alina, Nolan John P, White P Scott, Valdez Yolanda E, Hunt William C, Peyton Cheri L, Wheeler Cosette M
Abstract excerpt
BACKGROUND: Polymorphisms in the TNF-alpha promoter region have recently been shown to be associated with susceptibility to cervical cancer. Some polymorphisms have been reported to influence transcription for this cytokine. Altered local levels in the cervix may influence an individual's immune response, thereby affecting persistence of human papillomavirus (HPV) 16 infection, a primary etiological factor for...
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