Article
Saccharomyces cerevisiae histone H2A Ser122 facilitates DNA repair.
Genetics - 1 Jun 2005
Harvey Anne C, Jackson Stephen P, Downs Jessica A
Abstract excerpt
DNA repair takes place in the context of chromatin. Recently, it has become apparent that proteins that make up and modulate chromatin structure are involved in the detection and repair of DNA lesions. We previously demonstrated that Ser129 in the carboxyl-terminal tail of yeast histone H2A is important for double-strand-break responses. By undertaking a systematic site-directed mutagenesis approach, we...
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