Article
The Bcl I single nucleotide polymorphism of the human glucocorticoid receptor gene h-GR/NR3C1 promoter in patients with bronchial asthma: pilot study.
Molecular biology reports - 1 Aug 2011
Pietras Tadeusz, Panek Michał, Tworek Damian, Oszajca Katarzyna, Wujcik Radosław, Górski Paweł, Kuna Piotr, Szemraj Janusz
Abstract excerpt
Bcl I in the promoter polymorphism observed within h-GR/NR3C1 gene may play an important role in the development of bronchial asthma and resistance to GCs in the severe bronchial asthma. The aim of the investigation was to study the correlation between this h-GR/NR3C1 gene polymorphism and occurrence of asthma in the population of Polish asthmatics. Peripheral blood was obtained from 70 healthy volunteers and 59...
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