Article
Non-classical MHC-Ι genes in chronic hepatitis B and hepatocellular carcinoma.
Immunogenetics - 1 Mar 2012
Zhang Jian, Pan Lelin, Chen Luyan, Feng Xiaowen, Zhou Lin, Zheng Shusen
Abstract excerpt
The non-classical human leukocyte antigens (HLA)-E, HLA-G, and HLA-F have been shown to modulate immune responses. We examined whether non-classical HLA polymorphisms are associated with hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC). Fifteen Single-nucleotide polymorphisms (SNPs) in these non-classical class I alleles were investigated by ligase detection reaction. A fragment of 650 bp...
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