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Article

The role of non-classical and chain-related human leukocyte antigen polymorphisms in laryngeal squamous cell carcinoma.

Molecular biology reports - 1 Sept 2023

Ormandjieva Anastasia, Yordanov Stanislav, Stoyanov Hristo, Deliverska Elitsa, Shivarov Velizar, Ivanova Milena

Abstract excerpt

BACKGROUND: Laryngeal squamous cell carcinoma (LSCC) is the major pathological subtype of laryngeal cancer. It has been shown that alterations of the expression of non-classical human leukocyte antigens (HLA) and the chain-related MIC molecules by malignant cells can lead to escape from the immune system control and certain allele variants may participate in immune editing and therefore be associated with...

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PMID: 37418079
DOI: 10.1007/s11033-023-08629-5

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