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Article

Association of HLA-DQ and IFNL4 polymorphisms with susceptibility to hepatitis B virus infection and clearance.

Annals of hepatology - 1 Jan 2000

Fan Jia-Hao, Hou Si-Hui, Qing-Ling Li, Hu Jun, Peng Hong, Guo Jin-Jun

Abstract excerpt

UNLABELLED: Background and aim. Leukocyte antigen DQ (HLA-DQ) and interferon-λ4 (IFNL4) gene polymorphisms were associated with susceptibility to chronic hepatitis B and C virus infection. This study further confirmed that variants of these genes were associated with susceptibility and spontaneous clearance of HBV infection in a Chinese population. MATERIAL AND METHODS: A total of 1,069 subjects were recruited...

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PMID: 27236152

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