Article
A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans.
PLoS genetics - 1 Jan 2012
Qayyum Rehan, Snively Beverly M, Ziv Elad, Nalls Michael A, Liu Yongmei, Tang Weihong, Yanek Lisa R, Lange Leslie, Evans Michele K, Ganesh Santhi, Austin Melissa A, Lettre Guillaume, Becker Diane M, Zonderman Alan B, Singleton Andrew B, Harris Tamara B, Mohler Emile R, Logsdon Benjamin A, Kooperberg Charles, Folsom Aaron R, Wilson James G, Becker Lewis C, Reiner Alexander P
Abstract excerpt
Several genetic variants associated with platelet count and mean platelet volume (MPV) were recently reported in people of European ancestry. In this meta-analysis of 7 genome-wide association studies (GWAS) enrolling African Americans, our aim was to identify novel genetic variants associated with platelet count and MPV. For all cohorts, GWAS analysis was performed using additive models after adjusting for age,...
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