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Sex-specific differences in genetic and nongenetic determinants of mean platelet volume: results from the Gutenberg Health Study.

Blood - 14 Jan 2016

Panova-Noeva Marina, Schulz Andreas, Hermanns M Iris, Grossmann Vera, Pefani Evgenia, Spronk Henri M H, Laubert-Reh Dagmar, Binder Harald, Beutel Manfred, Pfeiffer Norbert, Blankenberg Stefan, Zeller Tanja, Münzel Thomas, Lackner Karl J, Ten Cate Hugo, Wild Philipp S

Abstract excerpt

Mean platelet volume (MPV), a measure of platelet size, is a potential biological marker of platelet function. To date, a comprehensive analysis including known genetic and nongenetic factors that determine MPV is still lacking. MPV has been evaluated in 15 010 individuals from the population-based Gutenberg Health Study. Genetic information was available for 4175 individuals. Our results showed that age (β,...

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PMID: 26518434
DOI: 10.1182/blood-2015-07-660308

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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