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Article

Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer.

BMC cancer - 7 Mar 2011

Newnham Genni M, Conron Matthew, McLachlan Sueanne, Dobrovic Alexander, Do Hongdo, Li Jason, Opeskin Kenneth, Thompson Natalie, Wright Gavin M, Thomas David M

Abstract excerpt

BACKGROUND: The aim of this study was to identify critical genes involved in non-small cell lung cancer (NSCLC) pathogenesis that may lead to a more complete understanding of this disease and identify novel molecular targets for use in the development of more effective therapies. METHODS: Both transcriptional and genomic profiling were performed on 69 resected NSCLC specimens and results correlated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21385341
DOI: 10.1186/1471-2407-11-93
PMCID: PMC3058106

Genes

KRAS

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