Article
Genetic classification of lung adenocarcinoma based on array-based comparative genomic hybridization analysis: its association with clinicopathologic features.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2005
Shibata Tatsuhiro, Uryu Satomi, Kokubu Akiko, Hosoda Fumie, Ohki Misao, Sakiyama Tokuki, Matsuno Yoshihiro, Tsuchiya Ryosuke, Kanai Yae, Kondo Tadashi, Imoto Issei, Inazawa Johji, Hirohashi Setsuo
Abstract excerpt
The array-based comparative genomic hybridization using microarrayed bacterial artificial chromosome clones allows high-resolution analysis of genome-wide copy number changes in tumors. To analyze the genetic alterations of primary lung adenocarcinoma in a high-throughput way, we used laser-capture microdissection of cancer cells and array comparative genomic hybridization focusing on 800 chromosomal loci...
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