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Comparison of Salmonella typhimurium TA102 with Escherichia coli WP2 tester strains.

Mutagenesis - 1 May 1990

Wilcox P, Naidoo A, Wedd D J, Gatehouse D G

Abstract excerpt

In 1982, Levin et al. published a paper describing a new Salmonella typhimurium strain, TA102, for detecting mutagenic agents that react preferentially with AT base pairs. This strain has an AT base pair at the critical mutation site within the hisG gene, which is located on a multicopy plasmid, pAQ1; the chromosomal copy of the hisG gene has been deleted. It also has an intact excision repair system, thus...

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PMID: 2200948
DOI: 10.1093/mutage/5.3.285

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