Article
Characterization of Trp(+) reversions in Escherichia coli strain WP2uvrA.
Mutagenesis - 1 Jul 2002
Ohta Toshihiro, Tokishita Shin-ichi, Tsunoi Rumi, Ohmae Satoru, Yamagata Hideo
Abstract excerpt
The Escherichia coli strain WP2uvrA is widely used in general mutagenicity screening tests because of its high sensitivity to many kinds of mutagens and it serves as a supplement to the standard Salmonella typhimurium tester strains. In contrast to Salmonella His(+) revertants, E.coli Trp(+) revertants have not been characterized at the molecular level. In this study we found that in the trpE65 allele of WP2uvrA...
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