Article
Comparison of sensitivity of Escherichia coli WP2 tester strains with and without tolC outer membrane transport protein mutation in detecting chemical mutagens.
Journal of UOEH - 1 Jun 2008
Araki Akihiro, Sasaki Toshiaki, Matsushima Taijiro
Abstract excerpt
We compared the sensitivity of new Escherichia coli tester strains having the TolC outer membrane transport protein mutation (tolC strain), viz., WP2tolC, WP2tolC/pKM101, WP2uvrA, tolC and WP2uvrA, tolC/pKMO101, with E. coli strains not carrying this mutation (non-tolC strain), i.e., WP2, WP2/pKM101, WP2uvrA and WP2uvrA/pKM101, by measuring the specific activity (revertants/mg) of mutagens using a preincubation...
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