Studies on the induction of gene mutations in bacterial and mammalian cells by the ring-opened benzene metabolites trans,trans-muconaldehyde and trans,trans-muconic acid.

doi:10.1093/mutage/5.3.263

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Article

Studies on the induction of gene mutations in bacterial and mammalian cells by the ring-opened benzene metabolites trans,trans-muconaldehyde and trans,trans-muconic acid.

Mutagenesis - 1 May 1990

Glatt H, Witz G

Abstract excerpt

t,t-Muconaldehyde and t,t-muconic acid have been investigated for the induction of gene mutations in Salmonella typhimurium (reversion of the his- strains TA97, TA98, TA100, TA102, TA104 and TA1535), Escherichia coli (reversion of the trp- strain WP2 uvrA) and Chinese hamster V79 cells (acquisiti...

Topics

Aldehydes
Animals
Benzene
Cells, Cultured
Cricetinae
Cricetulus
Escherichia coli
Fatty Acids, Unsaturated
Male
Mutagenicity Tests
Mutagens
Mutation
Rats
Rats, Inbred Strains
Sorbic Acid

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