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Article

Comparative mutagenicity of halomethanes and halonitromethanes in Salmonella TA100: structure-activity analysis and mutation spectra.

Mutation research - 4 Oct 2004

Kundu Bijit, Richardson Susan D, Granville Courtney A, Shaughnessy Daniel T, Hanley Nancy M, Swartz Paul D, Richard Ann M, DeMarini David M

Abstract excerpt

Halonitromethanes (HNMs) are a recently identified class of disinfection by-products (DPBs) in drinking water that are mutagenic in Salmonella and potent inducers of DNA strand breaks in mammalian cells. Here we compared the mutagenic potencies of the HNMs to those of their halomethane (HM) homologues by testing all nine HNMs and seven of the nine HMs (minus bromomethane and chloromethane) under the same...

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Identifiers

PMID: 15450430
DOI: 10.1016/j.mrfmmm.2004.05.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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