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Article

Mannose binding lectin gene (MBL2) functional polymorphisms are associated with systemic lupus erythematosus in southern Brazilians.

Human immunology - 1 Jun 2011

Sandrin-Garcia Paula, Brandão Lucas André Cavalcanti, Coelho Antônio Victor Campos, Guimarães Rafael Lima, Pancoto João Alexandre Trés, Segat Ludovica, Donadi Eduardo Antônio, de Lima-Filho José Luiz, Crovella Sergio

Abstract excerpt

Susceptibility to systemic lupus erythematosus (SLE) has been associated with immunologic, environmental, and genetic factors. To uncover a possible association between MBL2 gene polymorphisms and SLE, we analyzed functional polymorphisms in the promoter and first exon of the MBL2 gene in 134 Brazilian SLE patients and 101 healthy controls. Genotype and allele frequencies of MBL2 A/O polymorphism were...

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Identifiers

PMID: 21510992
DOI: 10.1016/j.humimm.2011.03.007

Genes

MBL2

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