Article
Lama1 mutations lead to vitreoretinal blood vessel formation, persistence of fetal vasculature, and epiretinal membrane formation in mice.
BMC developmental biology - 14 Oct 2011
Edwards Malia M, McLeod D Scott, Grebe Rhonda, Heng Céline, Lefebvre Olivier, Lutty Gerard A
Abstract excerpt
BACKGROUND: Valuable insights into the complex process of retinal vascular development can be gained using models with abnormal retinal vasculature. Two such models are the recently described mouse lines with mutations in Lama1, an important component of the retinal internal limiting membrane (IL...
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