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Article

Astrocytes follow ganglion cell axons to establish an angiogenic template during retinal development.

Glia - 1 Oct 2017

O'Sullivan Matthew L, Puñal Vanessa M, Kerstein Patrick C, Brzezinski Joseph A, Glaser Tom, Wright Kevin M, Kay Jeremy N

Abstract excerpt

Immature astrocytes and blood vessels enter the developing mammalian retina at the optic nerve head and migrate peripherally to colonize the entire retinal nerve fiber layer (RNFL). Retinal vascularization is arrested in retinopathy of prematurity (ROP), a major cause of bilateral blindness in children. Despite their importance in normal development and ROP, the factors that control vascularization of the retina...

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Source

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Identifiers

PMID: 28722174
DOI: 10.1002/glia.23189
PMCID: PMC5561467

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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