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Article

Hook2 is involved in the morphogenesis of the primary cilium

13 Oct 2011

Abstract excerpt

Primary cilia originate from the centrosome and play essential roles in several cellular, developmental, and pathological processes, but the underlying mechanisms of ciliogenesis are not fully understood. Given the involvement of the adaptor protein Hook2 in centrosomal homeostasis and protein transport to pericentrosomal aggresomes, we explored its role in ciliogenesis. We found that in human retinal epithelial...

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PMID: 21998199
DOI: 10.1091/mbc.e11-05-0405

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