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Article

Primary cilia and the DNA damage response: linking a cellular antenna and nuclear signals.

Biochemical Society transactions - 30 Apr 2021

Morrison Ciaran G

Abstract excerpt

The maintenance of genome stability involves integrated biochemical activities that detect DNA damage or incomplete replication, delay the cell cycle, and direct DNA repair activities on the affected chromatin. These processes, collectively termed the DNA damage response (DDR), are crucial for cell survival and to avoid disease, particularly cancer. Recent work has highlighted links between the DDR and the...

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PMID: 33843966
DOI: 10.1042/BST20200751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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