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Function of the Acrosomal Matrix: Zona Pellucida 3 Receptor (ZP3R/sp56) Is Not Essential for Mouse Fertilization1

14 Oct 2011

Abstract excerpt

In mammalian fertilization, sperm-zona pellucida binding is considered to be a critical aspect of gamete interaction. In this study, we examine the mouse sperm acrosomal matrix protein zona pellucida 3 receptor (ZP3R; formerly called sp56) because of our interest in defining the function of the acrosomal matrix, the particulate compartment within the sperm secretory acrosome. Using targeted deletion of the Zp3r...

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PMID: 21998167
DOI: 10.1095/biolreprod.111.095877

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