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Article

The molecular genetics of the zona pellucida: mouse mutations and infertility.

Molecular human reproduction - 1 Nov 1996

Rankin T, Dean J

Abstract excerpt

The zona pellucida is an extracellular matrix surrounding growing oocytes, ovulated eggs and the preimplantation embryo. After mediating the relatively species-specific events of fertilization, the zona pellucida provides a post-fertilization block to polyspermy and protects the growing embryo as it passes down the oviduct. The genes that encode the three zona pellucida proteins (ZP1, ZP2, ZP3) have been...

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Identifiers

PMID: 9237231
DOI: 10.1093/molehr/2.11.889

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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The molecular genetics of the zona pellucida: mouse mutations and infertility.PMID 9237231Read ↗

The mouse zona pellucida: folliculogenesis, fertility and pre-implantation development.Semantic proximity Read ↗

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Mice homozygous for an insertional mutation in the Zp3 gene lack a zona pellucida and are infertile.Semantic proximity Read ↗

Cracking the egg: increased complexity in the zona pellucidaSemantic proximity Read ↗

Influence of the zona pellucida of the mouse egg on folliculogenesis and fertility.Semantic proximity Read ↗

[The human zona pellucida: New genetic findings].Semantic proximity Read ↗

Reassessing the molecular biology of sperm–egg recognition with mouse geneticsSemantic proximity Read ↗

Zona Pellucida Genes and Proteins: Essential Players in Mammalian Oogenesis and FertilitySemantic proximity Read ↗

A heterozygous ZP2 mutation causes zona pellucida defects and female infertility in mouse and humanSemantic proximity Read ↗

Ovarian development in mice bearing homozygous or heterozygous null mutations in zona pellucida glycoprotein gene mZP3.Semantic proximity Read ↗

Identification of zona pellucida defects revealed a novel loss-of-function mutation in ZP2 in humans and rats.Semantic proximity Read ↗

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