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Article

Cracking the egg: increased complexity in the zona pellucida

11 Mar 2005

Abstract excerpt

A functional zona pellucida is critical for both fertilization and the early stages of embryo development. Recent data from genomic and proteomic studies have questioned our simplistic view of the zona as being composed of three proteins whose functions are clearly defined. In the human, for example, the zona pellucida is composed of four proteins, not three. The increased complexity of the zona pellucida in...

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PMID: 15760956
DOI: 10.1093/humrep/deh835

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