Article
Synchronous breast cancers with different morphologic and molecular phenotypes occurring in Lynch syndrome: what does the heterogeneity imply?
The American journal of surgical pathology - 1 Nov 2011
D'Arcy Clare, Wen Yong H, Stadler Zsofia K, Brogi Edi, Shia Jinru
Abstract excerpt
The increasingly widespread use of immunohistochemistry in the detection of DNA mismatch repair proteins has led to the observation of various unusual tumor types that occur in Lynch syndrome and exhibit mismatch repair protein deficiency. Understanding the clinical significance of such unusual tumors has become increasingly desirable. Here, we report a case of 2 synchronous breast cancers occurring in a...
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