Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry.

doi:10.1158/1078-0432.CCR-09-3058

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Article

Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 2010

Walsh Michael D, Buchanan Daniel D, Cummings Margaret C, Pearson Sally-Ann, Arnold Sven T, Clendenning Mark, Walters Rhiannon, McKeone Diane M, Spurdle Amanda B, Hopper John L, Jenkins Mark A, Phillips Kerry D, Suthers Graeme K, George Jill, Goldblatt Jack, Muir Amanda, Tucker Kathy, Pelzer Elise, Gattas Michael R, Woodall Sonja, Parry Susan, Macrae Finlay A, Haile Robert W, Baron John A, Potter John D, Le Marchand Loic, Bapat Bharati, Thibodeau Stephen N, Lindor Noralane M, McGuckin Michael A, Young Joanne P

Abstract excerpt

PURPOSE: The recognition of breast cancer as a spectrum tumor in Lynch syndrome remains controversial. The aim of this study was to explore features of breast cancers arising in Lynch syndrome families. EXPERIMENTAL DESIGN: This observational study involved 107 cases of breast cancer identified f...

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Identifiers

PMID: 20215533
DOI: 10.1158/1078-0432.CCR-09-3058
PMCID: PMC2848890

Genes

MLH1
MSH2
MSH6
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20215533-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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