Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Colorectal Carcinomas With Isolated Loss of PMS2 Staining by Immunohistochemistry

16 Jan 2018

Abstract excerpt

CONTEXT: - Isolated loss of PMS2 staining is an uncommon immunophenotype in colorectal carcinomas, accounting for approximately 4% of tumors with microsatellite instability. Limited information regarding these tumors is available in the literature. OBJECTIVE: - To compare the clinicopathologic features of colorectal carcinomas with isolated PMS2 loss by immunohistochemistry to those with other forms of mismatch...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Cancer Screening and Detection
Share to Genetic factors in colorectal cancer
Share to Multiple and Secondary Primary Cancers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29336605
DOI: 10.5858/arpa.2017-0156-oa

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Colorectal Carcinomas With Isolated Loss of PMS2 Staining by ImmunohistochemistryPMID 29336605Read ↗

Germline MLH1 Mutations Are Frequently Identified in Lynch Syndrome Patients With Colorectal and Endometrial Carcinoma Demonstrating Isolated Loss of PMS2 Immunohistochemical Expression.Semantic proximity Read ↗

Isolated Loss of PMS2 Expression in Colorectal Cancers: Frequency, Patient Age, and Familial AggregationSemantic proximity Read ↗

Characteristics of colorectal carcinoma patients with PMS2 defects detected by immunohistochemistrySemantic proximity Read ↗

Isolated Loss of PMS2 Immunohistochemical Expression is Frequently Caused by Heterogenous MLH1 Promoter Hypermethylation in Lynch Syndrome Screening for Endometrial Cancer Patients.Semantic proximity Read ↗

Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer.Semantic proximity Read ↗

The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations.Semantic proximity Read ↗

Abrupt Loss of MLH1 and PMS2 Expression in Endometrial CarcinomaSemantic proximity Read ↗

Germline mutations inPMS2andMLH1in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry CohortSemantic proximity Read ↗

Mismatch repair gene PMS2: disease-causing germline mutations are frequent in patients whose tumors stain negative for PMS2 protein, but paralogous genes obscure mutation detection and interpretation.Semantic proximity Read ↗

Homozygous PMS2 deletion causes a severe colorectal cancer and multiple adenoma phenotype without extraintestinal cancer.Semantic proximity Read ↗

Immunohistochemical "null" pattern of all four mismatch repair proteins in Lynch syndrome-associated small bowel adenocarcinoma: a case report and comprehensive genomic profiling.Semantic proximity Read ↗

Distinctive patterns of p53 protein expression and microsatellite instability in human colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.