Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unusual Mismatch Repair Immunohistochemical Patterns in Endometrial Carcinoma

17 May 2016

Abstract excerpt

Universal screening for Lynch syndrome through mismatch repair (MMR) immunohistochemistry (IHC) on tumor samples has brought to light several heterogenous MMR staining patterns. At our institution, a prospective study of universal Lynch syndrome screening using MMR IHC on 125 endometrial cancers (EC) led to the identification of subclonal loss of MMR protein expression within the tumor (n=9). We also interrogated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Cancer-related molecular mechanisms research
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27186853
DOI: 10.1097/pas.0000000000000663

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unusual Mismatch Repair Immunohistochemical Patterns in Endometrial CarcinomaPMID 27186853Read ↗

Endometrial Carcinomas With Subclonal Loss of Mismatch Repair ProteinsSemantic proximity Read ↗

Characterization of mismatch‐repair/microsatellite instability‐discordant endometrial cancersSemantic proximity Read ↗

A retrospective study of consistency between immunohistochemistry and polymerase chain reaction of microsatellite instability in endometrial cancerSemantic proximity Read ↗

Clinicopathologic Comparison of Lynch Syndrome-associated and "Lynch-like" Endometrial Carcinomas Identified on Universal Screening Using Mismatch Repair Protein Immunohistochemistry.Semantic proximity Read ↗

Universal Screening for Mismatch-Repair Deficiency in Endometrial Cancers to Identify Patients With Lynch Syndrome and Lynch-like SyndromeSemantic proximity Read ↗

Clinicopathologic characteristics and outcomes of endometrial Cancer patients with mismatch repair deficiency in the era of universal Lynch syndrome screening.Semantic proximity Read ↗

Abrupt Loss of MLH1 and PMS2 Expression in Endometrial CarcinomaSemantic proximity Read ↗

DNA Mismatch Repair–deficient Endometrial Carcinosarcomas Portend Distinct Clinical, Morphologic, and Molecular Features Compared With Traditional CarcinosarcomasSemantic proximity Read ↗

Clinicopathologic features of endometrial cancer with mismatch repair deficiencySemantic proximity Read ↗

Mismatch Repair Deficiency as a Predictive and Prognostic Biomarker in Endometrial Cancer: A Review on Immunohistochemistry Staining Patterns and Clinical ImplicationsSemantic proximity Read ↗

Universal screening for Lynch syndrome in endometrial cancers: frequency of germline mutations and identification of patients with Lynch-like syndrome.Semantic proximity Read ↗

Mismatch Repair Deficiency in Endometrial Cancer: Immunohistochemistry Staining and Clinical ImplicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.