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Article

ATP-binding cassette transporters as pharmacogenetic biomarkers for kidney transplantation.

Clinica chimica acta; international journal of clinical chemistry - 8 Sept 2012

Shuker Nauras, Bouamar Rachida, Weimar Willem, van Schaik Ron H N, van Gelder Teun, Hesselink Dennis A

Abstract excerpt

Immunosuppressive drugs used in organ transplantation are highly effective in preventing acute rejection. However, the clinical use of these drugs is complicated by the fact that they display highly variable pharmacokinetics and pharmacodynamics between individual patients. The influence of genetic variation on the interindividual variability in immunosuppressive drug disposition, efficacy, and toxicity has been...

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Share to Biomarkers, Pharmacological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ABCC2 gene

Share to Genetic Variation

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Share to Multidrug Resistance-Associated Protein 2

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 21996082
DOI: 10.1016/j.cca.2011.09.040

Genes

ABCB1
ABCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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