Article
Quantifying stability in gene list ranking across microarray derived clinical biomarkers.
BMC medical genomics - 14 Oct 2011
Schneckener Sebastian, Arden Nilou S, Schuppert Andreas
Abstract excerpt
BACKGROUND: Identifying stable gene lists for diagnosis, prognosis prediction, and treatment guidance of tumors remains a major challenge in cancer research. Microarrays measuring differential gene expression are widely used and should be versatile predictors of disease and other phenotypic data. However, gene expression profile studies and predictive biomarkers are often of low power, requiring numerous samples...
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