Article

Stable gene expression for normalisation and single-sample scoring

2020-05-05

Abstract excerpt

<h4>Background</h4> Transcriptomic signatures are useful in defining the molecular phenotypes of cells, tissues, and patient samples. Their most successful and widespread clinical application is the stratification of breast cancer patients into molecular (PAM50) subtypes. In most cases, gene expression signatures are developed using transcriptome-wide measurements, thus methods that match signatures to samples ty...

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Literature Corpus work: 1f4c2e1a-b02f-5ecb-a661-d5e50974fa1f
DOI: 10.1101/2020.05.04.077859

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