Article
On reliable discovery of molecular signatures.
BMC bioinformatics - 29 Jan 2009
Nilsson Roland, Björkegren Johan, Tegnér Jesper
Abstract excerpt
BACKGROUND: Molecular signatures are sets of genes, proteins, genetic variants or other variables that can be used as markers for a particular phenotype. Reliable signature discovery methods could yield valuable insight into cell biology and mechanisms of human disease. However, it is currently not clear how to control error rates such as the false discovery rate (FDR) in signature discovery. Moreover, signatures...
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