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Article

Host genetics in immune-mediated hepatitis C virus clearance.

Biomarkers in medicine - 1 Apr 2011

Schmidt Julia, Thimme Robert, Neumann-Haefelin Christoph

Abstract excerpt

Upon infection with hepatitis C virus (HCV), only few patients spontaneously clear the virus, while most patients develop chronic HCV infection. The host innate and adaptive immune response is believed to be the key determinant of viral clearance or persistence. Several host factors have been demonstrated to influence the efficiency of the antiviral immune response, including IL-28B polymorphisms, inhibitory...

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PMID: 21473719
DOI: 10.2217/bmm.11.19

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